Phenotypes associated with this allele

• Allele Symbol: C1galt1^tm1.1Staka
• Allele Name: targeted mutation 1.1, Satoru Takahashi
• Allele ID: MGI:5524266
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	C1galt1^tm1.1Staka/C1galt1^tm1.2Staka Tg(Mx1-cre)1Cgn/0	involves: C57BL/6 * C57BL/6J * CBA * DBA/2	MGI:5524268

Genotype
MGI:5524268

cn1

• Allelic Composition: C1galt1^tm1.1Staka/C1galt1^tm1.2Staka; Tg(Mx1-cre)1Cgn/0
• Genetic Background: involves: C57BL/6 * C57BL/6J * CBA * DBA/2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

hematopoietic system phenotype ( J:202276 )

N • pIpC-treated mice exhibit normal numbers of megakaryocytes in the bone marrow

abnormal megakaryocyte differentiation ( J:202276 )

• pIpC-treated mice exhibit abnormal morphology of terminally differentiated megakaryocytes

abnormal platelet morphology ( J:202276 )

• giant platelets with increased number of microtubule coils in pIpC-treated mice

thrombocytopenia ( J:202276 )

• severe in pIpC-treated mice whether or not mice are splenectomized

giant platelets ( J:202276 )

• in pIpC-treated mice

homeostasis/metabolism

increased bleeding time ( J:202276 )

• in pIpC-treated mice whether or not mice are splenectomized

cellular

abnormal megakaryocyte differentiation ( J:202276 )

• pIpC-treated mice exhibit abnormal morphology of terminally differentiated megakaryocytes