About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gata1tm1.1Yen
targeted mutation 1.1, Hsin-Fang Yang-Yen
MGI:5521597
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Gata1tm1.1Yen/Gata1tm1.1Yen involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N MGI:5521636
cx2
 		Cdkn1atm1Tyj/Cdkn1atm1Tyj
Gata1tm1.1Yen/Gata1tm1.1Yen 		involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6 * FVB/N MGI:5522831
cx3
 		Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Gata1tm1.1Yen/Gata1tm1.1Yen 		involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N MGI:5521638


Genotype
MGI:5521636
hm1
Allelic
Composition		 Gata1tm1.1Yen/Gata1tm1.1Yen
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gata1tm1.1Yen mutation (0 available); any Gata1 mutation (44 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
hematopoietic system phenotype ( J:200716 )
N
• mice exhibit normal peripheral blood composition
abnormal erythropoiesis ( J:200716 )
• erythrocyte-committed progenitors exhibit better survival in the absence of erythropoietin compared with wild-type cells
decreased erythroid progenitor cell number ( J:200716 )
• colony forming erythroid cells in the bone marrow




Genotype
MGI:5522831
cx2
Allelic
Composition		 Cdkn1atm1Tyj/Cdkn1atm1Tyj
Gata1tm1.1Yen/Gata1tm1.1Yen
Genetic
Background		 involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdkn1atm1Tyj mutation (3 available); any Cdkn1a mutation (60 available)
Gata1tm1.1Yen mutation (0 available); any Gata1 mutation (44 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
hematopoietic system phenotype ( J:200716 )
N
• the number of colony forming erythroid cells is rescued




Genotype
MGI:5521638
cx3
Allelic
Composition		 Bcl2l11tm1.1Ast/Bcl2l11tm1.1Ast
Gata1tm1.1Yen/Gata1tm1.1Yen
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bcl2l11tm1.1Ast mutation (4 available); any Bcl2l11 mutation (32 available)
Gata1tm1.1Yen mutation (0 available); any Gata1 mutation (44 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased erythroid progenitor cell number ( J:200716 )
• colony forming erythroid cells in the bone marrow




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory