Analysis Tools
growth/size/body
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• postnatal dwarfism in male, but not female, mice
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Allele Symbol Allele Name Allele ID |
Lin28btm1.1Gqda targeted mutation 1.1, George Q Daley MGI:5519055 |
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| Summary |
5 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• postnatal dwarfism in male, but not female, mice
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• mice exhibit normal growth when treated with tamoxifen at 7 to 9 days or 6 weeks of age
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• postnatal dwarfism in male, but not female, mice treated with tamoxifen at E15.5
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• mice die between E10.5 and E12.5
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• in 2 of 7 at E11.5
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• poor development
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• collapsed ventricle
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• indicated by fewer somites at E10.5 and open neural tube in some mice at E11.5
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• at E9.5 and E10.5
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• indicated by fewer somites at E10.5 and open neural tube in some mice at E11.5
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• at E9.5 and E10.5
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• in 2 of 7 at E11.5
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/07/2024 MGI 6.23 |
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