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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Lin28btm1Gqda
targeted mutation 1, George Q Daley
MGI:5519037
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Lin28btm1Gqda/Lin28btm1.1Gqda
Ndor1Tg(UBC-cre/ERT2)1Ejb/0
involves: 129S/SvEv * 129S4/SvJae * C57BL/6 MGI:5519073
cn2
Lin28btm1Gqda/Lin28btm1Gqda
Myf5tm1(cre)Mrc/Myf5+
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 MGI:5519076
cn3
Lin28btm1Gqda/Lin28btm1Gqda
Myf5tm1(cre)Mrc/Myf5+
Tsc1tm1Djk/Tsc1+
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 MGI:5519081


Genotype
MGI:5519073
cn1
Allelic
Composition
Lin28btm1Gqda/Lin28btm1.1Gqda
Ndor1Tg(UBC-cre/ERT2)1Ejb/0
Genetic
Background
involves: 129S/SvEv * 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lin28btm1.1Gqda mutation (1 available); any Lin28b mutation (22 available)
Lin28btm1Gqda mutation (0 available); any Lin28b mutation (22 available)
Ndor1Tg(UBC-cre/ERT2)1Ejb mutation (6 available); any Ndor1 mutation (32 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
growth/size/body
N
• mice exhibit normal growth when treated with tamoxifen at 7 to 9 days or 6 weeks of age
• postnatal dwarfism in male, but not female, mice treated with tamoxifen at E15.5




Genotype
MGI:5519076
cn2
Allelic
Composition
Lin28btm1Gqda/Lin28btm1Gqda
Myf5tm1(cre)Mrc/Myf5+
Genetic
Background
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lin28btm1Gqda mutation (0 available); any Lin28b mutation (22 available)
Myf5tm1(cre)Mrc mutation (1 available); any Myf5 mutation (17 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism

growth/size/body
• postnatal dwarfism in male, but not female, mice

muscle
N
• mice exhibit normal muscle histology




Genotype
MGI:5519081
cn3
Allelic
Composition
Lin28btm1Gqda/Lin28btm1Gqda
Myf5tm1(cre)Mrc/Myf5+
Tsc1tm1Djk/Tsc1+
Genetic
Background
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lin28btm1Gqda mutation (0 available); any Lin28b mutation (22 available)
Myf5tm1(cre)Mrc mutation (1 available); any Myf5 mutation (17 available)
Tsc1tm1Djk mutation (2 available); any Tsc1 mutation (69 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
growth/size/body
N
• male mice exhibit normal growth





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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory