Phenotypes associated with this allele

• Allele Symbol: Kif1b^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5505909
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Kif1b^tm1b(KOMP)Wtsi/Kif1b^tm1b(KOMP)Wtsi	C57BL/6N-Kif1b^tm1b(KOMP)Wtsi/J	MGI:5639390
ht2	Kif1b^tm1b(KOMP)Wtsi/Kif1b^+	C57BL/6N-Kif1b^tm1b(KOMP)Wtsi/J	MGI:5631239

Genotype
MGI:5639390

hm1

• Allelic Composition: Kif1b^{tm1b(KOMP)Wtsi}/Kif1b^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Kif1b^{tm1b(KOMP)Wtsi}/J
• Cell Lines: EPD0624_1_H07

Data Sources

IMPC Data for Kif1b

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

unresponsive to tactile stimuli ( J:211773 )

IMPC - JAX

cardiovascular system

hemorrhage ( J:211773 )

IMPC - JAX

craniofacial

abnormal facial morphology ( J:211773 )

IMPC - JAX

abnormal head shape ( J:211773 )

IMPC - JAX

abnormal outer ear morphology ( J:211773 )

IMPC - JAX

embryo

abnormal embryo size ( J:211773 )

IMPC - JAX

growth/size/body

abnormal facial morphology ( J:211773 )

IMPC - JAX

abnormal head shape ( J:211773 )

IMPC - JAX

abnormal outer ear morphology ( J:211773 )

IMPC - JAX

abnormal embryo size ( J:211773 )

IMPC - JAX

hearing/vestibular/ear

abnormal outer ear morphology ( J:211773 )

IMPC - JAX

limbs/digits/tail

abnormal limb morphology ( J:211773 )

IMPC - JAX

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

Genotype
MGI:5631239

ht2

• Allelic Composition: Kif1b^{tm1b(KOMP)Wtsi}/Kif1b⁺
• Genetic Background: C57BL/6N-Kif1b^{tm1b(KOMP)Wtsi}/J
• Cell Lines: EPD0624_1_H07

Data Sources

IMPC Data for Kif1b

behavior/neurological

decreased exploration in new environment ( J:211773 )

IMPC - JAX

decreased thigmotaxis ( J:211773 )

IMPC - JAX

increased startle reflex ( J:211773 )

♀

IMPC - JAX

hyperactivity ( J:211773 )

♀

IMPC - JAX

increased vertical activity ( J:211773 )

♀

IMPC - JAX

hematopoietic system

increased mean corpuscular hemoglobin concentration ( J:211773 )

♀

IMPC - JAX

homeostasis/metabolism

decreased blood urea nitrogen level ( J:211773 )

♀

IMPC - JAX

increased circulating sodium level ( J:211773 )

IMPC - JAX

increased circulating chloride level ( J:211773 )

♀

IMPC - JAX