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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Atp2b2Deaf11
deaf 11
MGI:5505456
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Atp2b2Deaf11/Atp2b2Deaf11 BALB/c-Atp2b2Deaf11 MGI:5505525
ht2
 		Atp2b2Deaf11/Atp2b2+ BALB/c-Atp2b2Deaf11 MGI:5505526
ht3
 		Atp2b2Deaf11/Atp2b2Deaf13 BALB/c-Atp2b2Deaf11/Atp2b2Deaf13 MGI:5505530


Genotype
MGI:5505525
hm1
Allelic
Composition		 Atp2b2Deaf11/Atp2b2Deaf11
Genetic
Background		 BALB/c-Atp2b2Deaf11
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atp2b2Deaf11 mutation (0 available); any Atp2b2 mutation (66 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Abnormal cochlear hair cells in Atp2b2Deaf11/Atp2b2Deaf11 and Atp2b2Deaf13/Atp2b2Deaf13 mice

hearing/vestibular/ear
impaired hearing ( J:199859 )
• profound at 4 weeks

behavior/neurological

nervous system




Genotype
MGI:5505526
ht2
Allelic
Composition		 Atp2b2Deaf11/Atp2b2+
Genetic
Background		 BALB/c-Atp2b2Deaf11
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atp2b2Deaf11 mutation (0 available); any Atp2b2 mutation (66 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hearing/vestibular/ear
increased or absent threshold for auditory brainstem response ( J:199859 )
• high frequency hearing loss at 4 weeks
• middle and high frequency hearing loss at 8 weeks
impaired hearing ( J:199859 )
• high frequency hearing loss at 4 weeks
• middle and high frequency hearing loss at 8 weeks

behavior/neurological




Genotype
MGI:5505530
ht3
Allelic
Composition		 Atp2b2Deaf11/Atp2b2Deaf13
Genetic
Background		 BALB/c-Atp2b2Deaf11/Atp2b2Deaf13
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atp2b2Deaf11 mutation (0 available); any Atp2b2 mutation (66 available)
Atp2b2Deaf13 mutation (0 available); any Atp2b2 mutation (66 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hearing/vestibular/ear
impaired hearing ( J:199859 )
• profound at 4 weeks




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory