All Phenotypes Igh<tm2.1(4E10)Nemz> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Igh^{tm2.1(4E10)Nemz}
targeted mutation 2.1, David Nemazee
MGI:5505305

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Igh^{tm2.1(4E10)Nemz}/Igh^{tm2.1(4E10)Nemz} Igk^{tm2.1(4E10)Nemz}/Igk^{tm2.1(4E10)Nemz}	involves: C57BL/6 * C57BL/6N * C57BL/6NTac * FVB/N	MGI:5505309

Allelic Composition	Igh^{tm2.1(4E10)Nemz}/Igh^{tm2.1(4E10)Nemz} Igk^{tm2.1(4E10)Nemz}/Igk^{tm2.1(4E10)Nemz}
Genetic Background	involves: C57BL/6 * C57BL/6N * C57BL/6NTac * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Igh^{tm2.1(4E10)Nemz} mutation (1 available); any Igh mutation (45 available)
Igk^{tm2.1(4E10)Nemz} mutation (1 available); any Igk mutation (31 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

decreased B cell number ( J:101977 )

• in the spleen

decreased IgG level ( J:101977 )

• low levels of IgG anti-gp41

decreased IgM level ( J:101977 )

• low levels of IgM anti-gp41

immune system