Phenotypes associated with this allele

• Allele Symbol: Rpl13a^tm1.1Mazu
• Allele Name: targeted mutation 1.1, Barsanjit Mazumder
• Allele ID: MGI:5502322
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Rpl13a^tm1.1Mazu/Rpl13a^tm1.1Mazu Lyz2^tm1(cre)Ifo/Lyz2^+	involves: C57BL/6	MGI:5502329

Genotype
MGI:5502329

cn1

• Allelic Composition: Rpl13a^tm1.1Mazu/Rpl13a^tm1.1Mazu; Lyz2^tm1(cre)Ifo/Lyz2⁺
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:194920 )

• reduced survival when challenged with lipopolysaccharide

respiratory system

abnormal lung morphology ( J:194920 )

• red blood cells in the bronchiolar and alveolar spaces of the lungs

tachypnea ( J:194920 )

• increased breathing rate

behavior/neurological

decreased locomotor activity ( J:194920 )

• reduced ambulatory activity

homeostasis/metabolism

increased blood urea nitrogen level ( J:194920 )

increased circulating aspartate transaminase level ( J:194920 )

abnormal cytokine level ( J:194920 )

• general increase in inflammatory cytokines

increased circulating tumor necrosis factor level ( J:194920 )

immune system

abnormal macrophage chemotaxis ( J:194920 )

• enhanced infiltration of peritoneum

• increases in the spleen and circulation

• increased infiltration of the kidneys

• increased infiltration of bronchiolar and alveolar spaces of the lungs

abnormal cytokine level ( J:194920 )

• general increase in inflammatory cytokines

increased circulating tumor necrosis factor level ( J:194920 )

cellular

abnormal macrophage chemotaxis ( J:194920 )

• enhanced infiltration of peritoneum

• increases in the spleen and circulation

• increased infiltration of the kidneys

• increased infiltration of bronchiolar and alveolar spaces of the lungs

hematopoietic system

abnormal macrophage chemotaxis ( J:194920 )

• enhanced infiltration of peritoneum

• increases in the spleen and circulation

• increased infiltration of the kidneys

• increased infiltration of bronchiolar and alveolar spaces of the lungs