Phenotypes associated with this allele

• Allele Symbol: Zfp148^tm1.1Jmer
• Allele Name: targeted mutation 1.1, Juanita L Merchant
• Allele ID: MGI:5502212
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Zfp148^tm1.1Jmer/Zfp148^tm1.1Jmer Tg(Vil1-cre)997Gum/0	involves: C57BL/6 * C57BL/6J * SJL	MGI:5502215

Genotype
MGI:5502215

cn1

• Allelic Composition: Zfp148^tm1.1Jmer/Zfp148^tm1.1Jmer; Tg(Vil1-cre)997Gum/0
• Genetic Background: involves: C57BL/6 * C57BL/6J * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

increased susceptibility to bacterial infection induced morbidity/mortality ( J:198847 )

• in mice infected with Salmonella typhimurium

immune system

increased inflammatory response ( J:198847 )

• slightly prior to infection

increased susceptibility to bacterial infection ( J:198847 )

• mice infected with Salmonella typhimurium exhibit increased weight loss, earlier lethality and increased colonic and systemic bacterial load compared with wild-type mice

increased susceptibility to bacterial infection induced morbidity/mortality ( J:198847 )

• in mice infected with Salmonella typhimurium

homeostasis/metabolism

decreased serotonin level ( J:198847 )

• in the enteroendocrine cells of the colons and plasma

growth/size/body

increased susceptibility to weight loss ( J:198847 )

• in mice infected with Salmonella typhimurium