Phenotypes associated with this allele

• Allele Symbol: Zbtb18^tm2.1Haok
• Allele Name: targeted mutation 2.1, Haruo Okado
• Allele ID: MGI:5502199
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Zbtb18^tm2.1Haok/Zbtb18^tm2.1Haok	involves: 129	MGI:5502208

Genotype
MGI:5502208

hm1

• Allelic Composition: Zbtb18^tm2.1Haok/Zbtb18^tm2.1Haok
• Genetic Background: involves: 129

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal neuron differentiation ( J:196306 )

• neurons accumulate under the subplate, fail to enter into the cortical plate and fail to undergo multipolar-to-bipolar transition

• however, cells exhibit normal cell-cycle exit

abnormal neuronal migration ( J:196306 )

• impaired in neurons from mice electroporated with a cre-expressing plasmid with cells arresting in the middle of the cortex

cellular

abnormal neuron differentiation ( J:196306 )

• neurons accumulate under the subplate, fail to enter into the cortical plate and fail to undergo multipolar-to-bipolar transition

• however, cells exhibit normal cell-cycle exit

abnormal neuronal migration ( J:196306 )

• impaired in neurons from mice electroporated with a cre-expressing plasmid with cells arresting in the middle of the cortex