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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ccbe1tm2.1Mlkn
targeted mutation 2.1, Mark L Kahn
MGI:5495677
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Ccbe1tm2.1Mlkn/Ccbe1tm2.1Mlkn
Tg(VAV1-cre)1Graf/0 		involves: 129 MGI:5495739
cn2
 		Ccbe1tm2.1Mlkn/Ccbe1tm2.1Mlkn
Ndor1Tg(UBC-cre/ERT2)1Ejb/0 		involves: 129 * C57BL/6 MGI:5495740


Genotype
MGI:5495739
cn1
Allelic
Composition		 Ccbe1tm2.1Mlkn/Ccbe1tm2.1Mlkn
Tg(VAV1-cre)1Graf/0
Genetic
Background		 involves: 129
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccbe1tm2.1Mlkn mutation (0 available); any Ccbe1 mutation (22 available)
Tg(VAV1-cre)1Graf mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:196696 )
• viable with no overt phenotypes and normal hematologic profiles




Genotype
MGI:5495740
cn2
Allelic
Composition		 Ccbe1tm2.1Mlkn/Ccbe1tm2.1Mlkn
Ndor1Tg(UBC-cre/ERT2)1Ejb/0
Genetic
Background		 involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccbe1tm2.1Mlkn mutation (0 available); any Ccbe1 mutation (22 available)
Ndor1Tg(UBC-cre/ERT2)1Ejb mutation (11 available); any Ndor1 mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
hematopoietic system phenotype ( J:196696 )
N
• following postnatal tamoxifen hematocrits and erythropoiesis following phlebotomy are similar to controls




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory