About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ccbe1tm2.1Mlkn
targeted mutation 2.1, Mark L Kahn
MGI:5495677
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Ccbe1tm2.1Mlkn/Ccbe1tm2.1Mlkn
Tg(VAV1-cre)1Graf/0 		involves: 129 MGI:5495739
cn2
 		Ccbe1tm2.1Mlkn/Ccbe1tm2.1Mlkn
Ndor1Tg(UBC-cre/ERT2)1Ejb/0 		involves: 129 * C57BL/6 MGI:5495740


Genotype
MGI:5495739
cn1
Allelic
Composition		 Ccbe1tm2.1Mlkn/Ccbe1tm2.1Mlkn
Tg(VAV1-cre)1Graf/0
Genetic
Background		 involves: 129
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccbe1tm2.1Mlkn mutation (0 available); any Ccbe1 mutation (19 available)
Tg(VAV1-cre)1Graf mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:196696 )
• viable with no overt phenotypes and normal hematologic profiles




Genotype
MGI:5495740
cn2
Allelic
Composition		 Ccbe1tm2.1Mlkn/Ccbe1tm2.1Mlkn
Ndor1Tg(UBC-cre/ERT2)1Ejb/0
Genetic
Background		 involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccbe1tm2.1Mlkn mutation (0 available); any Ccbe1 mutation (19 available)
Ndor1Tg(UBC-cre/ERT2)1Ejb mutation (6 available); any Ndor1 mutation (32 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
hematopoietic system phenotype ( J:196696 )
N
• following postnatal tamoxifen hematocrits and erythropoiesis following phlebotomy are similar to controls




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory