Phenotypes associated with this allele

• Allele Symbol: Rock2^tm2Liao
• Allele Name: targeted mutation 2, James K Liao
• Allele ID: MGI:5488746
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Rock2^tm2Liao/Rock2^tm2Liao Tg(Myh6-cre)2182Mds/?	involves: 129/Sv * C57BL/6	MGI:5491820

Genotype
MGI:5491820

cn1

• Allelic Composition: Rock2^tm2Liao/Rock2^tm2Liao; Tg(Myh6-cre)2182Mds/?
• Genetic Background: involves: 129/Sv * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

cardiovascular system phenotype ( J:196433 )

N • no anatomical or functional cardiac abnormalities before 25 weeks of age

N • increase in systolic blood pressure in response to Ang II is similar to controls

abnormal heart morphology ( J:196433 )

• less fibrosis than controls from Ang II infusion

abnormal heart size ( J:196433 )

• less cardiac hypertrophy than controls from Ang II infusion

• less cardiac hypertrophy due to trans aortic constriction