Phenotypes associated with this allele

• Allele Symbol: Kdf1⁺
• Allele Name: wild type
• Allele ID: MGI:5482554
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Kdf1^shd/Kdf1^+ Sfn^Er/Sfn^+	involves: C3HeB/FeJ * C57BL/6J	MGI:5559505

Genotype
MGI:5559505

cx1

• Allelic Composition: Kdf1^shd/Kdf1⁺; Sfn^Er/Sfn⁺
• Genetic Background: involves: C3HeB/FeJ * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, incomplete penetrance ( J:203995 )

• despite Mendelian numbers during embryonic development, only 1 mouse was obtained postnatally

integument

impaired skin barrier function ( J:203995 )

• in several areas, pronounced in the eyelids, ears, snout, digit/tail tips, chin and two dorsal stripes

abnormal epidermis stratum corneum morphology ( J:203995 )

• breaks in the cornified layer in dorsal stripes

• however, most regions exhibit normal cornified layers

thick epidermis ( J:203995 )

craniofacial

cleft palate ( J:203995 )

• in the one recovered mouse

oral atresia ( J:203995 )

• in the one recovered mouse

homeostasis/metabolism

impaired skin barrier function ( J:203995 )

• in several areas, pronounced in the eyelids, ears, snout, digit/tail tips, chin and two dorsal stripes

digestive/alimentary system

cleft palate ( J:203995 )

• in the one recovered mouse

growth/size/body

cleft palate ( J:203995 )

• in the one recovered mouse

oral atresia ( J:203995 )

• in the one recovered mouse