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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		th7m2
Harwell 7 mutation 2
MGI:5465008
Summary 5 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		th7m2/th7m2 Not Specified MGI:5465013
ht2
 		th7m2/t+ Not Specified MGI:5465171
cx3
 		Itpr3tf/Itpr3+
th7m2/t+ 		involves: BTBR MGI:5465015
cx4
 		T/T+
th7m2/t+
Itpr3tf/Itpr3+ 		involves: BTBR MGI:5465016
cx5
 		T/T+
th7m2/t+ 		Not Specified MGI:5465018


Genotype
MGI:5465013
hm1
Allelic
Composition		 th7m2/th7m2
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
th7m2 mutation (0 available); any t mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging




Genotype
MGI:5465171
ht2
Allelic
Composition		 th7m2/t+
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
th7m2 mutation (0 available); any t mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
transmission ratio distortion ( J:34190 )
• male mice exhibit moderately high transmission of th7m2




Genotype
MGI:5465015
cx3
Allelic
Composition		 Itpr3tf/Itpr3+
th7m2/t+
Genetic
Background		 involves: BTBR
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itpr3tf mutation (20 available); any Itpr3 mutation (178 available)
th7m2 mutation (0 available); any t mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:34190 )
N
• mice exhibit normal fertility




Genotype
MGI:5465016
cx4
Allelic
Composition		 T/T+
th7m2/t+
Itpr3tf/Itpr3+
Genetic
Background		 involves: BTBR
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itpr3tf mutation (20 available); any Itpr3 mutation (178 available)
T mutation (22 available); any T mutation (61 available)
th7m2 mutation (0 available); any t mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:34190 )
N
• mice exhibit normal fertility




Genotype
MGI:5465018
cx5
Allelic
Composition		 T/T+
th7m2/t+
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (22 available); any T mutation (61 available)
th7m2 mutation (0 available); any t mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
limbs/digits/tail




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory