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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Sox2tm1.1Vlcg
targeted mutation 1.1, Velocigene
MGI:5464908
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Sox2tm1.1Vlcg/Sox2tm1.1Vlcg involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NTac MGI:5464911
hm2
 		Sox2tm1.1Vlcg/Sox2tm1.1Vlcg involves: 129S6/SvEvTac * C57BL/6NTac MGI:5546253


Genotype
MGI:5464911
hm1
Allelic
Composition		 Sox2tm1.1Vlcg/Sox2tm1.1Vlcg
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sox2tm1.1Vlcg mutation (0 available); any Sox2 mutation (56 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Sox2tm1.2Vlcg/Sox2tm1.2Vlcg and Sox2tm1.1Vep/Sox2tm1.2Vlcg embryos form disorganized extraembryonic tissues, but fail to form the epiblast, phenocopying Sox2tm1.1Vep/Sox2tm1.1Vep embryos

behavior/neurological
behavior/neurological phenotype ( J:191980 )
N
• mice exhibit no abnormal behavior

growth/size/body
growth/size/body region phenotype ( J:191980 )
N
• mice exhibit normal body weight in adulthood




Genotype
MGI:5546253
hm2
Allelic
Composition		 Sox2tm1.1Vlcg/Sox2tm1.1Vlcg
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sox2tm1.1Vlcg mutation (0 available); any Sox2 mutation (56 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory