All Phenotypes Ebf2<tm3.1(Zfp423*)Reed> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ebf2^{tm3.1(Zfp423*)Reed}
targeted mutation 3.1, Randall R Reed
MGI:5461560

Summary

3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Ebf2^{tm3.1(Zfp423*)Reed}/Ebf2⁺	involves: 129 * C57BL/10J	MGI:5461562
cx2	Ebf2^{tm3.1(Zfp423*)Reed}/Ebf2⁺ Or8a1b^tm4Mom/Or8a1b⁺	involves: 129 * 129P2/OlaHsd * C57BL/10J	MGI:5461571
cx3	Ebf2^{tm3.1(Zfp423*)Reed}/Ebf2⁺ Or10a4^tm1Mom/Or10a4⁺	involves: 129 * 129P2/OlaHsd * C57BL/10J	MGI:5461572

Allelic Composition	Ebf2^{tm3.1(Zfp423*)Reed}/Ebf2⁺
Genetic Background	involves: 129 * C57BL/10J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ebf2^{tm3.1(Zfp423*)Reed} mutation (0 available); any Ebf2 mutation (30 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

nervous system phenotype ( J:190934 )

N	• development of olfactory sensory neurons is similar to controls

Allelic Composition	Ebf2^{tm3.1(Zfp423*)Reed}/Ebf2⁺ Or8a1b^tm4Mom/Or8a1b⁺
Genetic Background	involves: 129 * 129P2/OlaHsd * C57BL/10J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ebf2^{tm3.1(Zfp423*)Reed} mutation (0 available); any Ebf2 mutation (30 available)
Or8a1b^tm4Mom mutation (1 available); any Or8a1b mutation (35 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal olfactory sensory neuron morphology ( J:190934 )

• decrease in the number of labeled sensory neurons in the olfactory bulb

abnormal sensory neuron innervation pattern ( J:190934 )

• some labeled axons innervate aberrant extra glomeruli in the olfactory bulb

craniofacial

abnormal olfactory sensory neuron morphology ( J:190934 )

• decrease in the number of labeled sensory neurons in the olfactory bulb

respiratory system

abnormal olfactory sensory neuron morphology ( J:190934 )

• decrease in the number of labeled sensory neurons in the olfactory bulb

taste/olfaction

abnormal olfactory sensory neuron morphology ( J:190934 )

• decrease in the number of labeled sensory neurons in the olfactory bulb

growth/size/body

abnormal olfactory sensory neuron morphology ( J:190934 )

• decrease in the number of labeled sensory neurons in the olfactory bulb

Allelic Composition	Ebf2^{tm3.1(Zfp423*)Reed}/Ebf2⁺ Or10a4^tm1Mom/Or10a4⁺
Genetic Background	involves: 129 * 129P2/OlaHsd * C57BL/10J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ebf2^{tm3.1(Zfp423*)Reed} mutation (0 available); any Ebf2 mutation (30 available)
Or10a4^tm1Mom mutation (7 available); any Or10a4 mutation (22 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal olfactory sensory neuron morphology ( J:190934 )

• decrease in the number of labeled sensory neurons in the olfactory bulb

craniofacial

abnormal olfactory sensory neuron morphology ( J:190934 )

• decrease in the number of labeled sensory neurons in the olfactory bulb

respiratory system

abnormal olfactory sensory neuron morphology ( J:190934 )

• decrease in the number of labeled sensory neurons in the olfactory bulb

taste/olfaction

abnormal olfactory sensory neuron morphology ( J:190934 )

• decrease in the number of labeled sensory neurons in the olfactory bulb

growth/size/body

abnormal olfactory sensory neuron morphology ( J:190934 )

• decrease in the number of labeled sensory neurons in the olfactory bulb

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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