Or8a1b^tm4Mom
Targeted Allele Detail

Summary

• Symbol: Or8a1b^tm4Mom
• Name: olfactory receptor family 8 subfamily A member 1B; targeted mutation 4, Peter Mombaerts
• MGI ID: MGI:3051343
• Synonyms: M72-IRES-taulacZ, M72-lacZ, M72^TL, U43/Cre11
• Gene: Or8a1b Location: Chr9:37622644-37623576 bp, - strand Genetic Position: Chr9, 20.8 cM
• Alliance: Or8a1b^tm4Mom page

Olfactory sensory neurons axon targeting is perturbed in Ttc8^tm1Reed/Ttc8^tm1Reed Or8a1b^tm4Mom/Or8a1b⁺ mice

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:67661
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: An IRES-taulacZ-LTNL cassette was inserted downstream of the endogenous coding sequence. Transient Cre expression excised a floxed neo from the 3' end of the inserted cassette. (J:67661)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Or8a1b Mutation: 35 strains or lines available

References

• Original: J:67661 Zheng C, et al., Peripheral olfactory projections are differentially affected in mice deficient in a cyclic nucleotide-gated channel subunit. Neuron. 2000 Apr;26(1):81-91
• All: 18 reference(s)