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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Pkd1)248Som
transgene insertion 248, Stefan Somlo
MGI:5442173
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Prkcshtm1Som/Prkcshtm1Som
Tg(Pkd1)248Som/0
Tg(Cdh16-cre)91Igr/0 		involves: 129 * C57BL/6 * C57BL/6J * ICR * SJL/J MGI:5442310
cn2
 		Sec63tm1Som/Sec63tm1Som
Tg(Pkd1)248Som/0
Tg(Cdh16-cre)91Igr/0 		involves: 129 * C57BL/6 * C57BL/6J * ICR * SJL/J MGI:5442320
cn3
 		Pkd2tm3Som/Pkd2tm3Som
Tg(Pkd1)248Som/0
Tg(Pkhd1-cre)1Igr/0 		involves: C57BL/6J * SJL/J MGI:5442314


Genotype
MGI:5442310
cn1
Allelic
Composition		 Prkcshtm1Som/Prkcshtm1Som
Tg(Pkd1)248Som/0
Tg(Cdh16-cre)91Igr/0
Genetic
Background		 involves: 129 * C57BL/6 * C57BL/6J * ICR * SJL/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prkcshtm1Som mutation (0 available); any Prkcsh mutation (25 available)
Tg(Cdh16-cre)91Igr mutation (1 available)
Tg(Pkd1)248Som mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
renal/urinary system
kidney cyst ( J:188763 )
• mild at 6 months
dilated renal tubule ( J:188763 )
• mild at 6 months

growth/size/body
kidney cyst ( J:188763 )
• mild at 6 months




Genotype
MGI:5442320
cn2
Allelic
Composition		 Sec63tm1Som/Sec63tm1Som
Tg(Pkd1)248Som/0
Tg(Cdh16-cre)91Igr/0
Genetic
Background		 involves: 129 * C57BL/6 * C57BL/6J * ICR * SJL/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sec63tm1Som mutation (0 available); any Sec63 mutation (38 available)
Tg(Cdh16-cre)91Igr mutation (1 available)
Tg(Pkd1)248Som mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
renal/urinary system
kidney cyst ( J:188763 )
• mild at P45

growth/size/body
kidney cyst ( J:188763 )
• mild at P45




Genotype
MGI:5442314
cn3
Allelic
Composition		 Pkd2tm3Som/Pkd2tm3Som
Tg(Pkd1)248Som/0
Tg(Pkhd1-cre)1Igr/0
Genetic
Background		 involves: C57BL/6J * SJL/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pkd2tm3Som mutation (0 available); any Pkd2 mutation (85 available)
Tg(Pkd1)248Som mutation (0 available)
Tg(Pkhd1-cre)1Igr mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
renal/urinary system

growth/size/body
kidney cyst ( J:188763 )




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory