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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		b2b1163Clo
Bench to Bassinet Program (B2B/CVDC), mutation 1163 Cecilia Lo
MGI:5433408
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		b2b1163Clo/b2b1163Clo C57BL/6J-b2b1163Clo MGI:5433487


Genotype
MGI:5433487
hm1
Allelic
Composition		 b2b1163Clo/b2b1163Clo
Genetic
Background		 C57BL/6J-b2b1163Clo
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
b2b1163Clo mutation (1 available); any b2b1163Clo mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Mutant 1163-006-NA displays malpositioned heart with interrupted aorta and DORV (confirmed by EFIC imaging)

cardiovascular system

growth/size/body
heart left ventricle hypertrophy ( J:175213 )
heart right ventricle hypertrophy ( J:175213 )
polycystic kidney ( J:175213 )
heterotaxia ( J:175213 )

renal/urinary system

muscle

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
cystic kidney disease DOID:2975 J:175213
visceral heterotaxy DOID:0050545 OMIM:PS306955
 J:175213




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory