All Phenotypes Sptbn1<tm1.1Mnr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Sptbn1^tm1.1Mnr
targeted mutation 1.1, Matthew N Rasband
MGI:5431637

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Sptbn1^tm1.1Mnr/Sptbn1^tm1.1Mnr Tg(Nes-cre)1Kln/0	involves: 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL	MGI:5431704

Allelic Composition	Sptbn1^tm1.1Mnr/Sptbn1^tm1.1Mnr Tg(Nes-cre)1Kln/0
Genetic Background	involves: 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sptbn1^tm1.1Mnr mutation (1 available); any Sptbn1 mutation (139 available)
Tg(Nes-cre)1Kln mutation (4 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

postnatal lethality, incomplete penetrance ( J:186168 )

• most mice die by P14

• however, some mice survive for more than 5 months

nervous system

abnormal axon initial segment morphology ( J:186168 )

• severely disrupted

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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