All Phenotypes Prkra<rep> MGI Mouse

Phenotypes associated with this allele

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Prkra^rep/Prkra^rep	involves: C3HeB/FeJ * C57BL/6J	MGI:5430999
ht2	Prkra^rep/Prkra⁺	involves: C3HeB/FeJ * C57BL/6J	MGI:5431000

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Prkra^rep/Prkra^rep mice (right) show reduced pinna

craniofacial

abnormal temporal bone zygomatic process morphology ( J:185991 )

• the zygomatic process is relatively more robust than in wild-type mice

small mandibular condyloid process ( J:185991 )

• reduced

small mandibular coronoid process ( J:185991 )

• reduced

short nasal bone ( J:185991 )

• very short nasal bones

small ears ( J:185991 )

reproductive system

female infertility ( J:185991 )

growth/size/body

short nasal bone ( J:185991 )

• very short nasal bones

small ears ( J:185991 )

decreased body weight ( J:185991 )

• detectable at P7

postnatal growth retardation ( J:185991 )

hearing/vestibular/ear

small ears ( J:185991 )

skeleton

abnormal temporal bone zygomatic process morphology ( J:185991 )

• the zygomatic process is relatively more robust than in wild-type mice

small mandibular condyloid process ( J:185991 )

• reduced

small mandibular coronoid process ( J:185991 )

• reduced

short nasal bone ( J:185991 )

• very short nasal bones

respiratory system

short nasal bone ( J:185991 )

• very short nasal bones

Allelic Composition	Prkra^rep/Prkra⁺
Genetic Background	involves: C3HeB/FeJ * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prkra^rep mutation (1 available); any Prkra mutation (23 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

craniofacial

short nasal bone ( J:185991 )

• very short nasal bones

skeleton

short nasal bone ( J:185991 )

• very short nasal bones

growth/size/body

short nasal bone ( J:185991 )

• very short nasal bones

respiratory system

short nasal bone ( J:185991 )

• very short nasal bones

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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