All Phenotypes Pip5k1a<tm1.1Tba> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Pip5k1a^tm1.1Tba
targeted mutation 1.1, Tadashi Baba
MGI:5430936

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pip5k1a^tm1.1Tba/Pip5k1a^tm1.1Tba	involves: 129P2/OlaHsd	MGI:5430944
cx2	Pip5k1a^tm1.1Tba/Pip5k1a^tm1.1Tba Pip5k1b^tm1Tssk/Pip5k1b^tm1Tssk	involves: 129P2/OlaHsd	MGI:5430945

Allelic Composition	Pip5k1a^tm1.1Tba/Pip5k1a^tm1.1Tba
Genetic Background	involves: 129P2/OlaHsd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pip5k1a^tm1.1Tba mutation (1 available); any Pip5k1a mutation (69 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

lethality, incomplete penetrance ( J:185835 )

• fewer than expected mice are produce from crossing heterozygous mice

reproductive system

abnormal sperm midpiece morphology ( J:185835 )

asthenozoospermia ( J:185835 )

• slightly

reduced male fertility ( J:185835 )

impaired fertilization ( J:185835 )

decreased fertilization frequency ( J:185835 )

cellular

abnormal sperm midpiece morphology ( J:185835 )

asthenozoospermia ( J:185835 )

• slightly

Allelic Composition	Pip5k1a^tm1.1Tba/Pip5k1a^tm1.1Tba Pip5k1b^tm1Tssk/Pip5k1b^tm1Tssk
Genetic Background	involves: 129P2/OlaHsd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pip5k1a^tm1.1Tba mutation (1 available); any Pip5k1a mutation (69 available)
Pip5k1b^tm1Tssk mutation (1 available); any Pip5k1b mutation (43 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

abnormal reproductive system morphology ( J:185835 )

abnormal sperm midpiece morphology ( J:185835 )

coiled sperm flagellum ( J:185835 )

• some sperm exhibit tails around the head

detached sperm flagellum ( J:185835 )

• some sperm exhibit snapped flagellum necks

oligozoospermia ( J:185835 )

abnormal spermiation ( J:185835 )

decreased testis weight ( J:185835 )

abnormal reproductive system physiology ( J:185835 )

asthenozoospermia ( J:185835 )

male infertility ( J:185835 )

impaired fertilization ( J:185835 )

• absent

decreased fertilization frequency ( J:185835 )

• absent

endocrine/exocrine glands

decreased testis weight ( J:185835 )

cellular

abnormal sperm midpiece morphology ( J:185835 )

coiled sperm flagellum ( J:185835 )

• some sperm exhibit tails around the head

detached sperm flagellum ( J:185835 )

• some sperm exhibit snapped flagellum necks

oligozoospermia ( J:185835 )

abnormal spermiation ( J:185835 )

asthenozoospermia ( J:185835 )

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