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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Glstm2.1Sray
targeted mutation 2.1, Stephen Rayport
MGI:5430235
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Glstm2.1Sray/Glstm2.1Sray involves: 129S1/Sv * C57BL/6 * FVB/N MGI:5430236
cn2
 		Glstm2.1Sray/Gls+
Tg(CAG-cre/Esr1*)5Amc/0 		involves: 129S1/Sv * C57BL/6 * CBA MGI:5784520


Genotype
MGI:5430236
hm1
Allelic
Composition		 Glstm2.1Sray/Glstm2.1Sray
Genetic
Background		 involves: 129S1/Sv * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Glstm2.1Sray mutation (1 available); any Gls mutation (46 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:185797 )
• mice are viable, fertile and normal in size




Genotype
MGI:5784520
cn2
Allelic
Composition		 Glstm2.1Sray/Gls+
Tg(CAG-cre/Esr1*)5Amc/0
Genetic
Background		 involves: 129S1/Sv * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Glstm2.1Sray mutation (1 available); any Gls mutation (46 available)
Tg(CAG-cre/Esr1*)5Amc mutation (11 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
impaired behavioral response to amphetamine ( J:230564 )
• attenuated locomotor response to amphetamine in tamoxifen-treated mice as compared to controls
• amphetamine-induced hyperlocomotion is blocked in open field test
abnormal locomotor activation ( J:230564 )
• decrease in fine movements, but not rearing, following administration of amphetamine in tamoxifen-treated mice as compared to controls




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory