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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Fcgr4tm1.1Rav
targeted mutation 1.1, Jeffrey V Ravetch
MGI:5428684
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Fcgr4tm1.1Rav/Fcgr4tm1.1Rav involves: C57BL/6 MGI:5428687


Genotype
MGI:5428687
hm1
Allelic
Composition
Fcgr4tm1.1Rav/Fcgr4tm1.1Rav
Genetic
Background
involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fcgr4tm1.1Rav mutation (0 available); any Fcgr4 mutation (22 available)
phenotype observed in females
phenotype observed in males
N normal phenotype

Decreased susceptibility to induced arthritis in Fcgr4tm1.1Rav/Fcgr4tm1.1Rav mice

immune system
N
• mice exhibit normal IgG-dependent Arthus and IgE-dependent passive cutaneous anaphylaxis reaction

homeostasis/metabolism
• mice are protected from IgG-dependent induced nephrotoxic nephritis

skeleton





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory