About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cdk2tm1.1Jro
targeted mutation 1.1, James Roberts
MGI:5319654
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Cdk2tm1.1Jro/Cdk2tm1.1Jro involves: 129S1/SvlmJ * 129S4/SvJaeSor * C57BL/6 MGI:5319675
ht2
 		Cdk2tm1.1Jro/Cdk2+ involves: 129S1/SvlmJ * 129S4/SvJaeSor * C57BL/6 MGI:5319676


Genotype
MGI:5319675
hm1
Allelic
Composition		 Cdk2tm1.1Jro/Cdk2tm1.1Jro
Genetic
Background		 involves: 129S1/SvlmJ * 129S4/SvJaeSor * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdk2tm1.1Jro mutation (0 available); any Cdk2 mutation (16 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging

growth/size/body
decreased body weight ( J:183801 )
• slight

cellular
cellular phenotype ( J:183801 )
N
• mouse embryonic fibroblasts exhibit normal cell cycle progression




Genotype
MGI:5319676
ht2
Allelic
Composition		 Cdk2tm1.1Jro/Cdk2+
Genetic
Background		 involves: 129S1/SvlmJ * 129S4/SvJaeSor * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdk2tm1.1Jro mutation (0 available); any Cdk2 mutation (16 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:183801 )
N
• female mice exhibit normal fertility
reduced male fertility ( J:183801 )
• Background Sensitivity: mice on a mixed background exhibit reduced male fertility compared with mice backcrossed onto the 129S1/SmJ and C57BL/6 background (no generation number specified)

endocrine/exocrine glands

cellular




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory