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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Igh*-Mir125b-1)5Toki
transgene insertion 5, Toshio Kitamura
MGI:5317552
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
 		Tg(Igh*-Mir125b-1)5Toki/0 Not Specified MGI:5317565


Genotype
MGI:5317565
tg1
Allelic
Composition		 Tg(Igh*-Mir125b-1)5Toki/0
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
decreased tumor-free survival time ( J:178816 )
• 5 of 13 mice develop lethal lymphoid tumors by 50 weeks of age

neoplasm
increased lymphoma incidence ( J:178816 )
• 5 of 13 mice develop lethal lymphoid tumors by 50 weeks of age
• tumors cells in the bone marrow and peripheral blood exhibit morphologically lymphoblastic features

growth/size/body
enlarged spleen ( J:178816 )

hematopoietic system

immune system




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory