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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cav1tm1Pesch
targeted mutation 1, Philipp E Scherer
MGI:5316847
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Cav1tm1Pesch/Cav1tm1Pesch
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ 		FVB.Cg-Cav1tm1Pesch Speer6-ps1Tg(Alb-cre)21Mgn MGI:5316849


Genotype
MGI:5316849
cn1
Allelic
Composition		 Cav1tm1Pesch/Cav1tm1Pesch
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic
Background		 FVB.Cg-Cav1tm1Pesch Speer6-ps1Tg(Alb-cre)21Mgn
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cav1tm1Pesch mutation (0 available); any Cav1 mutation (29 available)
Speer6-ps1Tg(Alb-cre)21Mgn mutation (6 available); any Speer6-ps1 mutation (4 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased circulating glucose level ( J:182288 )
• small but significant reduction in fasted glucose levels
decreased circulating glycerol level ( J:182288 )
• following 3-mercaptopicolinic acid treatment

liver/biliary system
liver/biliary system phenotype ( J:182288 )
N
• fasting induced steatosis and glycerol induced glucose production are similar to wild-type mice




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory