All Phenotypes Tg(Hnf1a-RB1*)XMiu MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tg(Hnf1a-RB1*)XMiu
transgene insertion X, Naoyuki Miura
MGI:5312916

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(Hnf1a-RB1*)XMiu/?	Not Specified	MGI:5312919

Allelic Composition	Tg(Hnf1a-RB1*)XMiu/?
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

liver/biliary system

abnormal hepatocyte morphology ( J:180294 )

• hepatocyte dysplasia is detected at 8 months of age

• at 8 months of age some hepatocytes and nuclei are enlarged

increased liver adenoma incidence ( J:180294 )

• about 50% of mice develop liver adenomas with no sex difference detected

• neoplastic nodules are first detected after 11 months of age

neoplasm

increased liver adenoma incidence ( J:180294 )

• about 50% of mice develop liver adenomas with no sex difference detected

• neoplastic nodules are first detected after 11 months of age

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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