All Phenotypes Fzd4<tm1.1Lex> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Fzd4^tm1.1Lex
targeted mutation 1.1, Lexicon Genetics
MGI:5312687

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fzd4^tm1.1Lex/Fzd4^tm1.1Lex	involves: 129S5/SvEvBrd * C57BL/6	MGI:5312691

Allelic Composition	Fzd4^tm1.1Lex/Fzd4^tm1.1Lex
Genetic Background	involves: 129S5/SvEvBrd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fzd4^tm1.1Lex mutation (0 available); any Fzd4 mutation (33 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

cardiovascular system phenotype ( J:181399 )

N	• mice exhibit normal choriocapillaris

decreased angiogenesis ( J:181399 )

• the superficial vascular plexus exhibits decreased complexity and vascular progression towards the retinal periphery compared to in wild-type mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/30/2025 MGI 6.24