All Phenotypes Slc6a3<tm1.1Jaja> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Slc6a3^tm1.1Jaja
targeted mutation 1.1, Jonathan A Javitch
MGI:5310749

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Slc6a3^tm1.1Jaja/Slc6a3^tm1.1Jaja	B6.129-Slc6a3^tm1.1Jaja	MGI:5310793

Allelic Composition	Slc6a3^tm1.1Jaja/Slc6a3^tm1.1Jaja
Genetic Background	B6.129-Slc6a3^tm1.1Jaja

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc6a3^tm1.1Jaja mutation (0 available); any Slc6a3 mutation (66 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

mortality/aging ( J:180517 )

N	• mice exhibit normal survival rate

reproductive system

reproductive system phenotype ( J:180517 )

N	• mice exhibit normal lactation

nervous system

decreased susceptibility to dopaminergic neuron neurotoxicity ( J:180517 )

• mice are resistant to paraquat-induced dopamine neuron neurotoxicity but decreased dopamine levels compared with wild-type mice

homeostasis/metabolism

decreased susceptibility to dopaminergic neuron neurotoxicity ( J:180517 )

• mice are resistant to paraquat-induced dopamine neuron neurotoxicity but decreased dopamine levels compared with wild-type mice

decreased dopamine level ( J:180517 )

• in paraquat-treated mice

cellular

decreased susceptibility to dopaminergic neuron neurotoxicity ( J:180517 )

• mice are resistant to paraquat-induced dopamine neuron neurotoxicity but decreased dopamine levels compared with wild-type mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/07/2024 MGI 6.23