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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Notch1tm1.1(cre/ERT2)Sat
targeted mutation 1.1, Spyros Artavanis-Tsakonas
MGI:5304912
Summary 2 genotypes


Genotype
MGI:5304922
hm1
Allelic
Composition		 Notch1tm1.1(cre/ERT2)Sat/Notch1tm1.1(cre/ERT2)Sat
Genetic
Background		 C57BL/6-Notch1tm1.1(cre/ERT2)Sat
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Notch1tm1.1(cre/ERT2)Sat mutation (0 available); any Notch1 mutation (115 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality ( J:179632 )
• homozygotes die during embryogenesis, like Notch1tm1Grid embryos




Genotype
MGI:5304923
ht2
Allelic
Composition		 Notch1tm1.1(cre/ERT2)Sat/Notch1+
Genetic
Background		 C57BL/6-Notch1tm1.1(cre/ERT2)Sat
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Notch1tm1.1(cre/ERT2)Sat mutation (0 available); any Notch1 mutation (115 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:179632 )
• heterozygotes are viable and fertile




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory