Phenotypes associated with this allele

• Allele Symbol: Ngfr^tm1.1Vk
• Allele Name: targeted mutation 1.1, Vesa Kaartinen
• Allele ID: MGI:5301291
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ngfr^tm1.1Vk/Ngfr^tm1.1Vk	involves: 129S2/SvPas * FVB/N	MGI:5301303
cn2	Ngfr^tm1.1Vk/Ngfr^tm1.1Vk H2az2^Tg(Wnt1-cre)11Rth/H2az2^+	involves: 129S2/SvPas * C57BL/6J * CBA/J * FVB/N	MGI:5301302

Genotype
MGI:5301303

hm1

• Allelic Composition: Ngfr^tm1.1Vk/Ngfr^tm1.1Vk
• Genetic Background: involves: 129S2/SvPas * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

normal phenotype

no abnormal phenotype detected ( J:178666 )

• mice are viable and fertile, and did not display any overt phenotypes

Genotype
MGI:5301302

cn2

• Allelic Composition: Ngfr^tm1.1Vk/Ngfr^tm1.1Vk; H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺
• Genetic Background: involves: 129S2/SvPas * C57BL/6J * CBA/J * FVB/N

nervous system

abnormal sciatic nerve morphology ( J:178666 )

• sciatic nerves exhibit reduced diameter with fewer small diameter axon bundles and a lower number of small diameter unmyelinated and lightly-myelinated axons compared with wild-type mice

behavior/neurological

limb grasping ( J:178666 )

cardiovascular system

cardiovascular system phenotype ( J:178666 )

N • mice exhibit normal vasodilatation

growth/size/body

growth/size/body region phenotype ( J:178666 )

N • mice exhibit normal growth