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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ngfrtm1.1Vk
targeted mutation 1.1, Vesa Kaartinen
MGI:5301291
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ngfrtm1.1Vk/Ngfrtm1.1Vk involves: 129S2/SvPas * FVB/N MGI:5301303
cn2
 		Ngfrtm1.1Vk/Ngfrtm1.1Vk
H2az2Tg(Wnt1-cre)11Rth/H2az2+ 		involves: 129S2/SvPas * C57BL/6J * CBA/J * FVB/N MGI:5301302


Genotype
MGI:5301303
hm1
Allelic
Composition		 Ngfrtm1.1Vk/Ngfrtm1.1Vk
Genetic
Background		 involves: 129S2/SvPas * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ngfrtm1.1Vk mutation (1 available); any Ngfr mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:178666 )
• mice are viable and fertile, and did not display any overt phenotypes




Genotype
MGI:5301302
cn2
Allelic
Composition		 Ngfrtm1.1Vk/Ngfrtm1.1Vk
H2az2Tg(Wnt1-cre)11Rth/H2az2+
Genetic
Background		 involves: 129S2/SvPas * C57BL/6J * CBA/J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H2az2Tg(Wnt1-cre)11Rth mutation (2 available); any H2az2 mutation (26 available)
Ngfrtm1.1Vk mutation (1 available); any Ngfr mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal sciatic nerve morphology ( J:178666 )
• sciatic nerves exhibit reduced diameter with fewer small diameter axon bundles and a lower number of small diameter unmyelinated and lightly-myelinated axons compared with wild-type mice

behavior/neurological

cardiovascular system
cardiovascular system phenotype ( J:178666 )
N
• mice exhibit normal vasodilatation

growth/size/body
growth/size/body region phenotype ( J:178666 )
N
• mice exhibit normal growth




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory