About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pdcd10tm1Arte
targeted mutation 1, TaconicArtemis
MGI:5297592
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Pdcd10tm1Arte/Pdcd10tm1Arte
Tg(Cdh5-cre/ERT2)1Rha/0 		involves: C57BL/6 MGI:5297596


Genotype
MGI:5297596
cn1
Allelic
Composition		 Pdcd10tm1Arte/Pdcd10tm1Arte
Tg(Cdh5-cre/ERT2)1Rha/0
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pdcd10tm1Arte mutation (0 available); any Pdcd10 mutation (18 available)
Tg(Cdh5-cre/ERT2)1Rha mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal brain vasculature morphology ( J:177584 )
• mice injected with tamoxifen at P1 develop cerebral cavernous malformation lesions within the cerebellum
abnormal retina vasculature morphology ( J:177584 )
• mice injected with tamoxifen at P1 develop cerebral cavernous malformation lesions within the periphery of the retina

nervous system
abnormal brain vasculature morphology ( J:177584 )
• mice injected with tamoxifen at P1 develop cerebral cavernous malformation lesions within the cerebellum

vision/eye
abnormal retina vasculature morphology ( J:177584 )
• mice injected with tamoxifen at P1 develop cerebral cavernous malformation lesions within the periphery of the retina




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory