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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Krit1tm1Arte
targeted mutation 1, TaconicArtemis
MGI:5297591
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Krit1tm1Arte/Krit1tm1Arte
Tg(Cdh5-cre/ERT2)1Rha/0 		involves: C57BL/6 MGI:5297595


Genotype
MGI:5297595
cn1
Allelic
Composition		 Krit1tm1Arte/Krit1tm1Arte
Tg(Cdh5-cre/ERT2)1Rha/0
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Krit1tm1Arte mutation (0 available); any Krit1 mutation (35 available)
Tg(Cdh5-cre/ERT2)1Rha mutation (5 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal brain vasculature morphology ( J:177584 )
• mice injected with tamoxifen at P1 develop cerebral cavernous malformation lesions within the cerebellum
abnormal retina vasculature morphology ( J:177584 )
• mice injected with tamoxifen at P1 develop cerebral cavernous malformation lesions within the periphery of the retina

nervous system
abnormal brain vasculature morphology ( J:177584 )
• mice injected with tamoxifen at P1 develop cerebral cavernous malformation lesions within the cerebellum

vision/eye
abnormal retina vasculature morphology ( J:177584 )
• mice injected with tamoxifen at P1 develop cerebral cavernous malformation lesions within the periphery of the retina




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory