Phenotypes associated with this allele

• Allele Symbol: Itgb1^tm10.1Ref
• Allele Name: targeted mutation 10.1, Reinhard Fassler
• Allele ID: MGI:5296845
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Itgb1^tm10.1Ref/Itgb1^tm10.1Ref	involves: 129S1/Sv * 129X1/SvJ	MGI:5430796
ht2	Itgb1^tm9.1Ref/Itgb1^tm10.1Ref	involves: 129S1/Sv * 129X1/SvJ	MGI:5296858

Genotype
MGI:5430796

hm1

• Allelic Composition: Itgb1^tm10.1Ref/Itgb1^tm10.1Ref
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

lethality, complete penetrance ( J:185558 )

• authors state that mice exhibit identical phenotype as observed in embryo

abnormal embryo development ( J:185558 )

• authors state that mice exhibit identical phenotype as observed in

Genotype
MGI:5296858

ht2

• Allelic Composition: Itgb1^tm9.1Ref/Itgb1^tm10.1Ref
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ

normal phenotype

no abnormal phenotype detected ( J:177979 )

• mice are viable and fertile with no obvious phenotype

integument

integument phenotype ( J:176453 )

N • keratinocyte adhesion is normal

neoplasm

neoplasm ( J:176453 )

N • TPA-treated mice exhibit normal tumorigenesis

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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