All Phenotypes S100a8<tm1Hogg> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

S100a8^tm1Hogg
targeted mutation 1, Nancy Hogg
MGI:5296777

Summary

2 genotypes

Allelic Composition	S100a8^tm1Hogg/S100a8^tm1Hogg
Genetic Background	B6.129P2-S100a8^tm1Hogg

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
S100a8^tm1Hogg mutation (0 available); any S100a8 mutation (7 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

• fewer than expected embryos are found at E2.5, E3.5, and E4.5 suggesting lethality occurs before the 8 cell stage

• none present at birth

• no embryos survive past implantation

• tetraploid complementation fails to rescue lethality

Allelic Composition	S100a8^tm1Hogg/S100a8^tm1Hogg
Genetic Background	involves: 129P2/OlaHsd * C57BL/6J * CD-1

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
S100a8^tm1Hogg mutation (0 available); any S100a8 mutation (7 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

• fewer than expected embryos are found at E4.5

• none present at birth

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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