S100a8^tm1Hogg
Targeted Allele Detail

Summary

• Symbol: S100a8^tm1Hogg
• Name: S100 calcium binding protein A8 (calgranulin A); targeted mutation 1, Nancy Hogg
• MGI ID: MGI:5296777
• Gene: S100a8 Location: Chr3:90576378-90577341 bp, + strand Genetic Position: Chr3, 39.9 cM, cytoband F1-F2
• Alliance: S100a8^tm1Hogg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:177483
• Parent Cell Line: GK129 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A lacZ neo cassette with stop codons in all three reading frames was inserted into exon 2 via homologous recombination. (J:177483)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any S100a8 Mutation: 7 strains or lines available

References

• Original: J:177483 Baker JR, et al., Distinct roles for S100a8 in early embryo development and in the maternal deciduum. Dev Dyn. 2011 Sep;240(9):2194-203
• All: 2 reference(s)