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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gt(ROSA)26Sortm1(H1/tetO-RNAi:Pion)Pggd
targeted mutation 1, Paul Greengard
MGI:5294908
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Gt(ROSA)26Sortm1(H1/tetO-RNAi:Pion)Pggd/Gt(ROSA)26Sor+
Tg(APPswe,PSEN1dE9)85Dbo/0 		involves: 129S6/SvEvTac * C3H * C57BL/6 MGI:5295743


Genotype
MGI:5295743
cx1
Allelic
Composition		 Gt(ROSA)26Sortm1(H1/tetO-RNAi:Pion)Pggd/Gt(ROSA)26Sor+
Tg(APPswe,PSEN1dE9)85Dbo/0
Genetic
Background		 involves: 129S6/SvEvTac * C3H * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(H1/tetO-RNAi:Pion)Pggd mutation (0 available); any Gt(ROSA)26Sor mutation (1046 available)
Tg(APPswe,PSEN1dE9)85Dbo mutation (8 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
amyloid beta deposits ( J:163997 )
• doxycycline-treated mice exhibit fewer amyloid plaques compared with un-induced mice

homeostasis/metabolism
amyloid beta deposits ( J:163997 )
• doxycycline-treated mice exhibit fewer amyloid plaques compared with un-induced mice




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory