All Phenotypes Kiss1r<tm1.1(cre)Uboe> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Kiss1r^{tm1.1(cre)Uboe}
targeted mutation 1.1, Ulrich Boehm
MGI:5052305

Summary

3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Kiss1r^{tm1.1(cre)Uboe}/Kiss1r⁺	involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL	MGI:5052331
cn2	Gt(ROSA)26Sor^tm1(DTA)Riet/Gt(ROSA)26Sor⁺ Kiss1r^{tm1.1(cre)Uboe}/Kiss1r⁺	involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * SJL	MGI:5052332
cn3	Gt(ROSA)26Sor^{tm1(HBEGF)Awai}/Gt(ROSA)26Sor⁺ Kiss1r^{tm1.1(cre)Uboe}/Kiss1r⁺	involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL	MGI:5052333

Allelic Composition	Kiss1r^{tm1.1(cre)Uboe}/Kiss1r⁺
Genetic Background	involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kiss1r^{tm1.1(cre)Uboe} mutation (0 available); any Kiss1r mutation (21 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

normal phenotype

no abnormal phenotype detected ( J:173936 )

• mice are viable with normal fertility

Allelic Composition	Gt(ROSA)26Sor^tm1(DTA)Riet/Gt(ROSA)26Sor⁺ Kiss1r^{tm1.1(cre)Uboe}/Kiss1r⁺
Genetic Background	involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sor^tm1(DTA)Riet mutation (0 available); any Gt(ROSA)26Sor mutation (1046 available)
Kiss1r^{tm1.1(cre)Uboe} mutation (0 available); any Kiss1r mutation (21 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

reproductive system phenotype ( J:173936 )

N	• female mice exhibit normal onset of puberty, ovalutory cyclicity, and fertile

decreased ovary weight ( J:173936 )

abnormal vagina development ( J:173936 )

• female mice exhibit slightly prolonged phases of cornification compared with wild-type mice

nervous system

decreased neuron number ( J:173936 )

• the number of gonadotrophin-releasing hormone neurons in the hypothalamus of female mice is decreased compared to in wild-type mice

endocrine/exocrine glands

decreased ovary weight ( J:173936 )

Allelic Composition	Gt(ROSA)26Sor^{tm1(HBEGF)Awai}/Gt(ROSA)26Sor⁺ Kiss1r^{tm1.1(cre)Uboe}/Kiss1r⁺
Genetic Background	involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sor^{tm1(HBEGF)Awai} mutation (4 available); any Gt(ROSA)26Sor mutation (1046 available)
Kiss1r^{tm1.1(cre)Uboe} mutation (0 available); any Kiss1r mutation (21 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

reproductive system phenotype ( J:173936 )

N	• diphtheria-treated mice exhibit normal ovalutory cyclicity and fertility

nervous system

decreased neuron number ( J:173936 )

• diphtheria-treated mice exhibit ablation of Kiss1r+ and gonadotrophin-releasing hormone neurons

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