Analysis Tools|
Allele Symbol Allele Name Allele ID |
Leprtm1.1Rll targeted mutation 1.1, Rudolph L Leibel MGI:5049781 |
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| Summary |
3 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• whether fed standard chow or a high-fat diet, mice exhibit normal weight and composition
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| N |
• whether fed standard chow or a high-fat diet, mice exhibit normal energy expenditure
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
Increased susceptibility to E. histolytica infection in Leprtm1.1Rll/Leprtm1.1Rll mice
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• E. histolytica-infected mice exhibit increased infection, more severe epithelial ulceration, and greater intestinal epithelial cell apoptosis compared to in similarly treated wild-type mice
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• in E. histolytica-infected mice
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• in E. histolytica-infected mice
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• E. histolytica-infected mice exhibit increased infection, more severe epithelial ulceration, and greater intestinal epithelial cell apoptosis compared to in similarly treated wild-type mice
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• in E. histolytica-infected mice
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• in E. histolytica-infected mice
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/30/2025 MGI 6.24 |
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