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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Upk2-cre)1Rkl
transgene insertion 1, Raghu Kalluri
MGI:5014304
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Trp53tm1Brn/Trp53tm1Brn
Tg(Upk2-cre)1Rkl/0 		involves: 129P2/OlaHsd * C57BL/6 * FVB MGI:5014309


Genotype
MGI:5014309
cn1
Allelic
Composition		 Trp53tm1Brn/Trp53tm1Brn
Tg(Upk2-cre)1Rkl/0
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Upk2-cre)1Rkl mutation (1 available)
Trp53tm1Brn mutation (20 available); any Trp53 mutation (238 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
renal/urinary system
renal/urinary system phenotype ( J:173505 )
N
• mice exhibit normal bladder morphology and vascularization

neoplasm
neoplasm ( J:173505 )
N
• mice do not exhibit bladder carcinoma

cardiovascular system
cardiovascular system phenotype ( J:173505 )
N
• mice exhibit normal bladder vascularization




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory