All Phenotypes Cux2<tm2.1(cre)Mull> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Cux2^{tm2.1(cre)Mull}
targeted mutation 2.1, Ulrich Mueller
MGI:5014175

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Dab1^tm1.1Mull/Dab1^tm1.1Mull Cux2^{tm2.1(cre)Mull}/Cux2⁺	involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * SJL	MGI:5141433

Allelic Composition	Dab1^tm1.1Mull/Dab1^tm1.1Mull Cux2^{tm2.1(cre)Mull}/Cux2⁺
Genetic Background	involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cux2^{tm2.1(cre)Mull} mutation (1 available); any Cux2 mutation (43 available)
Dab1^tm1.1Mull mutation (0 available); any Dab1 mutation (77 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

nervous system phenotype ( J:174747 )

N	• mice exhibit normal splitting of the cortical preplate

abnormal neuronal migration ( J:174747 )

• late-born neurons are mislocalized deep within the cortex compared to in control mice

• however, the relative position of early-born neurons is normal

abnormal neocortex morphology ( J:174747 )

• neocortical lamination is disrupted compared to in control mice

cellular

abnormal neuronal migration ( J:174747 )

• late-born neurons are mislocalized deep within the cortex compared to in control mice

• however, the relative position of early-born neurons is normal

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/07/2024 MGI 6.23