All Phenotypes Cux2<tm2.1(cre)Mull> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Cux2^{tm2.1(cre)Mull}
targeted mutation 2.1, Ulrich Mueller
MGI:5014175

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Dab1^tm1.1Mull/Dab1^tm1.1Mull Cux2^{tm2.1(cre)Mull}/Cux2⁺	involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * SJL	MGI:5141433

Allelic Composition	Dab1^tm1.1Mull/Dab1^tm1.1Mull Cux2^{tm2.1(cre)Mull}/Cux2⁺
Genetic Background	involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cux2^{tm2.1(cre)Mull} mutation (1 available); any Cux2 mutation (44 available)
Dab1^tm1.1Mull mutation (0 available); any Dab1 mutation (78 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

nervous system phenotype ( J:174747 )

N	• mice exhibit normal splitting of the cortical preplate

abnormal neuronal migration ( J:174747 )

• late-born neurons are mislocalized deep within the cortex compared to in control mice

• however, the relative position of early-born neurons is normal

abnormal neocortex morphology ( J:174747 )

• neocortical lamination is disrupted compared to in control mice

cellular

abnormal neuronal migration ( J:174747 )

• late-born neurons are mislocalized deep within the cortex compared to in control mice

• however, the relative position of early-born neurons is normal

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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