About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Birc3tm1Rbr
targeted mutation 1, Robert Brink
MGI:5013652
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Birc2tm1Rbr/Birc2tm1Rbr
Birc3tm1Rbr/Birc3tm1Rbr
Cd19tm1(cre)Cgn/Cd19+ 		involves: 129P2/OlaHsd * C57BL/6 * NZB MGI:5013716
cx2
 		Birc2tm1.1Rbr/Birc2tm1.1Rbr
Birc3tm1Rbr/Birc3tm1Rbr 		involves: BALB/cJ * C57BL/6 MGI:5319372
cx3
 		Birc2tm1Rbr/Birc2tm1Rbr
Birc3tm1Rbr/Birc3tm1Rbr 		involves: C57BL/6 MGI:5319371


Genotype
MGI:5013716
cn1
Allelic
Composition		 Birc2tm1Rbr/Birc2tm1Rbr
Birc3tm1Rbr/Birc3tm1Rbr
Cd19tm1(cre)Cgn/Cd19+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * NZB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Birc2tm1Rbr mutation (0 available); any Birc2 mutation (33 available)
Birc3tm1Rbr mutation (0 available); any Birc3 mutation (29 available)
Cd19tm1(cre)Cgn mutation (12 available); any Cd19 mutation (57 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:172843 )
N
• mice exhibit no differences in spleen or lymph node size or in the numbers or phenotype of the B cells within these peripheral lymphoid tissues compared with wild-type mice




Genotype
MGI:5319372
cx2
Allelic
Composition		 Birc2tm1.1Rbr/Birc2tm1.1Rbr
Birc3tm1Rbr/Birc3tm1Rbr
Genetic
Background		 involves: BALB/cJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Birc2tm1.1Rbr mutation (0 available); any Birc2 mutation (33 available)
Birc3tm1Rbr mutation (0 available); any Birc3 mutation (29 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:182515 )
• mice are viable with no reproductive or developmental defects




Genotype
MGI:5319371
cx3
Allelic
Composition		 Birc2tm1Rbr/Birc2tm1Rbr
Birc3tm1Rbr/Birc3tm1Rbr
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Birc2tm1Rbr mutation (0 available); any Birc2 mutation (33 available)
Birc3tm1Rbr mutation (0 available); any Birc3 mutation (29 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
10/07/2025
MGI 6.24 		The Jackson Laboratory