About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Golga2tm1(KOMP)Vlcg
targeted mutation 1, Velocigene
MGI:5008102
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Golga2tm1(KOMP)Vlcg/Golga2tm1(KOMP)Vlcg involves: C57BL/6NTac MGI:6362718


Genotype
MGI:6362718
hm1
Allelic
Composition
Golga2tm1(KOMP)Vlcg/Golga2tm1(KOMP)Vlcg
Genetic
Background
involves: C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Golga2tm1(KOMP)Vlcg mutation (0 available); any Golga2 mutation (53 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• pups are born at only 40% of the expected number

respiratory system
• lung tissues show autophagosomal forming structures
• lungs show several smaller sized secreted lamellar bodies suggesting a phenotype of discharged lamellar bodies
• autophagy-induced fibrosis
• decrease in levels of surfactant lipids

liver/biliary system
• liver tissues show autophagosomal forming structures that partially wrap the mitochondria with the double-membraned phagophore
• increased densities of hepatic cells
• autophagy-induced fibrosis

growth/size/body
• in males but not females
• in males and females

hematopoietic system

immune system





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/14/2024
MGI 6.23
The Jackson Laboratory