About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Nxph4tm1Lex
targeted mutation 1, Lexicon Pharmaceuticals
MGI:5007268
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Nxph4tm1Lex/Nxph4tm1Lex involves: 129S5/SvEvBrd * C57BL/6J MGI:5430938


Genotype
MGI:5430938
hm1
Allelic
Composition		 Nxph4tm1Lex/Nxph4tm1Lex
Genetic
Background		 involves: 129S5/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nxph4tm1Lex mutation (2 available); any Nxph4 mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased circulating triglyceride level ( J:171883 )
• female homozygous mutant mice exhibited a decreased mean serum triglyceride level
increased urine nitrite level ( J:171883 )
• homozygous mutants exhibit nitrituria

renal/urinary system
increased urine nitrite level ( J:171883 )
• homozygous mutants exhibit nitrituria




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory