Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kdm4btm1.1Okad mutation
(0 available);
any
Kdm4b mutation
(54 available)
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normal phenotype
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• mice are born in Mendelian ratio and display no abnormalities
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kdm4btm1.1Okad mutation
(0 available);
any
Kdm4b mutation
(54 available)
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endocrine/exocrine glands
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• mammary gland epithelial cells exposed to a cre-expressing retrovirus exhibit decreased proliferation compared with control cells
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integument
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• mammary gland epithelial cells exposed to a cre-expressing retrovirus exhibit decreased proliferation compared with control cells
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cellular
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• mammary gland epithelial cells exposed to a cre-expressing retrovirus exhibit decreased proliferation compared with control cells
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kdm4btm1.1Okad mutation
(0 available);
any
Kdm4b mutation
(54 available)
Tg(MMTV-cre)1Mam mutation
(1 available)
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Defective mammary gland development in Kdm4btm1.1Okad/Kdm4btm1.1Okad Tg(MMTV-cre)1Mam/0 mice
integument
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• mammary gland development is delayed with reduced branching compared to in wild-type mice
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• mammary gland branching is reduced compared to in wild-type mice
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endocrine/exocrine glands
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• mammary gland development is delayed with reduced branching compared to in wild-type mice
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• mammary gland branching is reduced compared to in wild-type mice
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