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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Dstntm1.1Wit
targeted mutation 1.1, Walter Witke
MGI:4943283
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Dstntm1.1Wit/Dstntm1.1Wit involves: BALB/cJ MGI:4943293
cn2
 		Cfl1tm1.1Wit/Cfl1+
Dstntm1.1Wit/Dstntm1.1Wit
Tg(Nes-cre)1Kln/0 		involves: 129 * BALB/cJ * C57BL/6 * SJL MGI:4943294


Genotype
MGI:4943293
hm1
Allelic
Composition		 Dstntm1.1Wit/Dstntm1.1Wit
Genetic
Background		 involves: BALB/cJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dstntm1.1Wit mutation (0 available); any Dstn mutation (45 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
abnormal cornea morphology ( J:125317 )
• mild hyperplasia

nervous system
nervous system phenotype ( J:125317 )
N
• mice exhibit normal brain development and morphology




Genotype
MGI:4943294
cn2
Allelic
Composition		 Cfl1tm1.1Wit/Cfl1+
Dstntm1.1Wit/Dstntm1.1Wit
Tg(Nes-cre)1Kln/0
Genetic
Background		 involves: 129 * BALB/cJ * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cfl1tm1.1Wit mutation (0 available); any Cfl1 mutation (29 available)
Dstntm1.1Wit mutation (0 available); any Dstn mutation (45 available)
Tg(Nes-cre)1Kln mutation (4 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:125317 )
• mice are viable and phenotypically normal




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory