Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Srgap3tm1Ssod mutation
(0 available);
any
Srgap3 mutation
(62 available)
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nervous system
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• following transfection with GFP-cre at DIV9, neurons exhibit a reduction in dendritic filopodia compared with wild-type mice
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• following transfection with GFP-cre at DIV5, spine density is reduced with a reduction in density of mushroom-shaped and thin spines compared to in wild-type mice
• however, spine density is normal when transfection at DIV9
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Srgap3tm1.1Ssod mutation
(0 available);
any
Srgap3 mutation
(62 available)
Srgap3tm1Ssod mutation
(0 available);
any
Srgap3 mutation
(62 available)
Tg(Thy1-cre/ERT2,-EYFP)VGfng mutation
(1 available)
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nervous system
N |
• tamoxifen-treated mice exhibit normal spine density
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Srgap3tm1Ssod mutation
(0 available);
any
Srgap3 mutation
(62 available)
Tg(Nes-cre)1Kln mutation
(4 available)
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behavior/neurological
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• mice exhibit impaired long term memory in a novel recognition, water maze, and passive avoidance assay compared with wild-type mice
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• mice exhibit impaired long term memory in a novel recognition, water maze, and passive avoidance assay compared with wild-type mice
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• mice exhibit impaired long term memory in a novel recognition, water maze, and passive avoidance assay compared with wild-type mice
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• mice exhibit impaired long term memory in a novel recognition, water maze, and passive avoidance assay compared with wild-type mice
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