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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Nes-cre/ERT2)#Kag
transgene insertion, Ryoichiro Kageyama
MGI:4941327
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Ptbp1tm1Nobu/Ptbp1tm2Nobu
Tg(Nes-cre/ERT2)#Kag/0 		involves: 129P2/OlaHsd * C57BL/6 MGI:5585415
cn2
 		Smc3tm1.1Toshi/Smc3tm1.1Toshi
Tg(Nes-cre/ERT2)#Kag/0 		involves: C57BL/6 * C57BL/6J MGI:7489857


Genotype
MGI:5585415
cn1
Allelic
Composition		 Ptbp1tm1Nobu/Ptbp1tm2Nobu
Tg(Nes-cre/ERT2)#Kag/0
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptbp1tm1Nobu mutation (0 available); any Ptbp1 mutation (36 available)
Ptbp1tm2Nobu mutation (0 available); any Ptbp1 mutation (36 available)
Tg(Nes-cre/ERT2)#Kag mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:213479 )
N
• mice treated with tamoxifen at E16.5 exhibit mature ependymal cells on the ventricular wall of the dorsal cortex at P10




Genotype
MGI:7489857
cn2
Allelic
Composition		 Smc3tm1.1Toshi/Smc3tm1.1Toshi
Tg(Nes-cre/ERT2)#Kag/0
Genetic
Background		 involves: C57BL/6 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Smc3tm1.1Toshi mutation (0 available); any Smc3 mutation (46 available)
Tg(Nes-cre/ERT2)#Kag mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
enlarged brain ventricles ( J:242006 )
• mice treated with tamoxifen at E10.5 and fixed with PFA at E18.5 exhibit enlarged ventricles




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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory