About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Anp32etm1Mak
targeted mutation 1, Tak Mak
MGI:4867888
Summary 9 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Anp32etm1Mak/Anp32etm1Mak involves: 129P2/OlaHsd * C57BL/6 MGI:4867890
cn2
 		Anp32etm1Mak/Anp32etm1Mak
Cfdp1tm1Dkwpd/Cfdp1tm2.1Dkwpd
E2f1Tg(Wnt1-cre)2Sor/E2f1+ 		involves: 129 * C3H * C57BL/6 MGI:7711577
cx3
 		Anp32btm1Mak/Anp32btm1Mak
Anp32etm1Mak/Anp32etm1Mak 		involves: 129P2/OlaHsd * C57BL/6 MGI:5003066
cx4
 		Anp32atm1Mak/Anp32atm1Mak
Anp32btm1Mak/Anp32btm1Mak
Anp32etm1Mak/Anp32etm1Mak 		involves: 129P2/OlaHsd * C57BL/6 MGI:5003067
cx5
 		Anp32atm1Mak/Anp32atm1Mak
Anp32btm1Mak/Anp32btm1Mak
Anp32etm1Mak/Anp32e+ 		involves: 129P2/OlaHsd * C57BL/6 MGI:5003068
cx6
 		Anp32atm1Mak/Anp32a+
Anp32btm1Mak/Anp32btm1Mak
Anp32etm1Mak/Anp32etm1Mak 		involves: 129P2/OlaHsd * C57BL/6 MGI:5003069
cx7
 		Anp32atm1Mak/Anp32atm1Mak
Anp32btm1Mak/Anp32b+
Anp32etm1Mak/Anp32etm1Mak 		involves: 129P2/OlaHsd * C57BL/6 MGI:5003070
cx8
 		Anp32atm1Mak/Anp32a+
Anp32btm1Mak/Anp32btm1Mak
Anp32etm1Mak/Anp32e+ 		involves: 129P2/OlaHsd * C57BL/6 MGI:5003071
cx9
 		Anp32atm1Mak/Anp32atm1Mak
Anp32etm1Mak/Anp32etm1Mak 		involves: 129P2/OlaHsd * C57BL/6 MGI:4867891


Genotype
MGI:4867890
hm1
Allelic
Composition		 Anp32etm1Mak/Anp32etm1Mak
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Anp32etm1Mak mutation (1 available); any Anp32e mutation (21 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:166683 )
• mice exhibit are viable and fertile with no specific pathologies




Genotype
MGI:7711577
cn2
Allelic
Composition		 Anp32etm1Mak/Anp32etm1Mak
Cfdp1tm1Dkwpd/Cfdp1tm2.1Dkwpd
E2f1Tg(Wnt1-cre)2Sor/E2f1+
Genetic
Background		 involves: 129 * C3H * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Anp32etm1Mak mutation (1 available); any Anp32e mutation (21 available)
Cfdp1tm1Dkwpd mutation (0 available); any Cfdp1 mutation (121 available)
Cfdp1tm2.1Dkwpd mutation (0 available); any Cfdp1 mutation (121 available)
E2f1Tg(Wnt1-cre)2Sor mutation (2 available); any E2f1 mutation (28 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal intracellular organelle physiology ( J:349245 )
N
• H2A.Z and RCC1 levels at the major satellite repeats are increased in rescue mice relative to both conditional mutant mice wild-type for Anp32e and wild-type controls

craniofacial
craniofacial phenotype ( J:349245 )
N
• loss of Anp32e expression largely rescues the craniofacial phenotype seen in conditional mutant mice wild-type for Anp32e
• maxilla and mandible are mineralized unlike in conditional mutant mice wild-type for Anp32e




Genotype
MGI:5003066
cx3
Allelic
Composition		 Anp32btm1Mak/Anp32btm1Mak
Anp32etm1Mak/Anp32etm1Mak
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Anp32btm1Mak mutation (1 available); any Anp32b mutation (101 available)
Anp32etm1Mak mutation (1 available); any Anp32e mutation (21 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
preweaning lethality, incomplete penetrance ( J:172042 )
• very few mice survive to weaning




Genotype
MGI:5003067
cx4
Allelic
Composition		 Anp32atm1Mak/Anp32atm1Mak
Anp32btm1Mak/Anp32btm1Mak
Anp32etm1Mak/Anp32etm1Mak
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Anp32atm1Mak mutation (1 available); any Anp32a mutation (57 available)
Anp32btm1Mak mutation (1 available); any Anp32b mutation (101 available)
Anp32etm1Mak mutation (1 available); any Anp32e mutation (21 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
preweaning lethality, complete penetrance ( J:172042 )
• no mice survive to weaning




Genotype
MGI:5003068
cx5
Allelic
Composition		 Anp32atm1Mak/Anp32atm1Mak
Anp32btm1Mak/Anp32btm1Mak
Anp32etm1Mak/Anp32e+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Anp32atm1Mak mutation (1 available); any Anp32a mutation (57 available)
Anp32btm1Mak mutation (1 available); any Anp32b mutation (101 available)
Anp32etm1Mak mutation (1 available); any Anp32e mutation (21 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
preweaning lethality, complete penetrance ( J:172042 )
• no mice survive to weaning




Genotype
MGI:5003069
cx6
Allelic
Composition		 Anp32atm1Mak/Anp32a+
Anp32btm1Mak/Anp32btm1Mak
Anp32etm1Mak/Anp32etm1Mak
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Anp32atm1Mak mutation (1 available); any Anp32a mutation (57 available)
Anp32btm1Mak mutation (1 available); any Anp32b mutation (101 available)
Anp32etm1Mak mutation (1 available); any Anp32e mutation (21 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
preweaning lethality, complete penetrance ( J:172042 )
• no mice survive to weaning




Genotype
MGI:5003070
cx7
Allelic
Composition		 Anp32atm1Mak/Anp32atm1Mak
Anp32btm1Mak/Anp32b+
Anp32etm1Mak/Anp32etm1Mak
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Anp32atm1Mak mutation (1 available); any Anp32a mutation (57 available)
Anp32btm1Mak mutation (1 available); any Anp32b mutation (101 available)
Anp32etm1Mak mutation (1 available); any Anp32e mutation (21 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:172042 )
N
• expected number of mice survive to weaning




Genotype
MGI:5003071
cx8
Allelic
Composition		 Anp32atm1Mak/Anp32a+
Anp32btm1Mak/Anp32btm1Mak
Anp32etm1Mak/Anp32e+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Anp32atm1Mak mutation (1 available); any Anp32a mutation (57 available)
Anp32btm1Mak mutation (1 available); any Anp32b mutation (101 available)
Anp32etm1Mak mutation (1 available); any Anp32e mutation (21 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
preweaning lethality, complete penetrance ( J:172042 )
• no mice survive to weaning




Genotype
MGI:4867891
cx9
Allelic
Composition		 Anp32atm1Mak/Anp32atm1Mak
Anp32etm1Mak/Anp32etm1Mak
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Anp32atm1Mak mutation (1 available); any Anp32a mutation (57 available)
Anp32etm1Mak mutation (1 available); any Anp32e mutation (21 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:166683 )
N
• mice exhibit normal viability

reproductive system
reproductive system phenotype ( J:166683 )
N
• mice exhibit normal fertility




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory